Summary: DOACs were associated with a lower risk of CRNM bleeding in patients ≥120 to <140 kg compared to warfarin.
Outcomes* Unadjusted† Adjusted†,‡
HR 95% CI P value HR 95% CI P value
CRNM bleed            
≥140 kg 1.06 0.73-1.55 .76 1.12 0.76-1.64 .58
≥120 to <140 kg 0.72 0.56-0.92 .0085 0.71 0.56-0.92 .0082
≥100 to <120 kg 0.95 0.82-1.11 .52 0.98 0.84-1.15 .82
≥60 to <100 kg 0.89 0.82-0.98 .01 0.95 0.87-1.05 .30
<60 kg 0.98 0.70-1.38 .91 1.06 0.74-1.50 .75
1|2|3|4|5|6|7|8|9|10|11|12