VTE*

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Apixaban Randomized
Controlled Clinical Trial Data
Agnelli G (N Engl J Med. 2013)
AMPLIFY weight and BMI subgroup analysis
Cohen AT (Adv Ther. 2021)
AMPLIFY post hoc analysis Extremes of body weight and exposure
Agnelli G (N Engl J Med. 2013)
AMPLIFY-EXT weight subgroup analysis
Real-World Data
Cohen A (J Clin Med. 2021)
Effectiveness and safety of apixaban vs. warfarin
in VTE patients with obesity and morbid obesity.
Perino AC (Circ Cardiovasc Qual Outcomes.
2021
)
Anti coagulation and outcomes by weight/BMI in VTE from Veterans Health Administration.
Crouch A (Pharmacotherapy. 2022)
Multi-center retrospective study evaluating the efficacy and safety of apixaban versus warfarin
for treatment of venous thromboembolism in
patients with severe obesity.
Kushnir M (Lancet Haematol. 2019)
Efficacy and safety of direct oral factor Xa inhibitors compared with warfarin in patients with morbid obesity: a single-centre, retrospective analysis of chart data.