Weight ≤60 kg Weight >60 to <100 kg Weight ≥100 to <120 kg Weight ≥120 kg
Total
N = 476		 Apix
N = 231		 E/W
n = 245		 Total
n = 3868		 Apix
n = 1932		 E/W
n = 1936		 Total
N = 750		 Apix
n = 378		 E/W
n = 372		 Total
n = 290		 Apix
n = 144		 E/W
n = 146
Clinical presentation of VTE, n (%)
Provoked 67 (14.1) 34 (14.7) 33 (13.5) 368 (9.5) 188 (9.7) 180 (9.3) 80 (10.7) 42 (11.1) 38 (10.2) 27 (9.3) 8 (5.6) 19 (13.0)
Unprovoked 409 (85.9) 197 (85.3) 212 (86.5) 3497 (90.4) 1744 (90.3) 1753 (90.5) 668 (89.1) 334 (88.4) 334 (89.8) 262 (90.3) 135 (93.8) 127 (87.0)
Not reported 0 (0.0) 0 (0.0) 0 (0.0) 3 (<0.1) 0 (0.0) 3 (0.2) 2 (0.3) 2 (0.5) 0 (0.0) 1 (0.3) 1 (0.7) 0 (0.0)
Risk factors, n (%)
Active cancer 18 (3.8) 9 (3.9) 9 (3.7) 104 (2.7) 47 (2.4) 57 (2.9) 14 (1.9) 6 (1.6) 8 (2.2) 7 (2.4) 4 (2.8) 3 (2.1)
Persistent or permanent immobility 33 (6.9) 18 (7.8) 15 (6.1) 246 (6.4) 138 (7.1) 108 (5.6) 46 (6.1) 23 (6.1) 23 (6.2) 21 (7.3) 8 (5.6) 13 (8.9)
Previous VTE 42 (8.8) 22 (9.5) 20 (8.2) 620 (16.0) 327 (16.9) 293 (15.2) 149 (19.9) 81 (21.5) 68 (18.3) 59 (20.4) 32 (22.4) 27 (18.5)
Known thrombophilia 8 (1.7) 5 (2.2) 3 (1.2) 96 (2.5) 55 (2.8) 41 (2.1) 21 (2.8) 10 (2.7) 11 (3.0) 7 (2.4) 4 (2.8) 3 (2.1)
Cigarette smoking 103 (21.6) 48 (20.8) 55 (22.4) 893 (23.1) 452 (23.4) 441 (22.8) 195 (26.1) 93 (24.7) 102 (27.4) 86 (29.8) 38 (26.6) 48 (32.9)
Diabetes mellitus 27 (5.7) 17 (7.4) 10 (4.1) 435 (11.3) 224 (11.6) 211 (10.9) 128 (17.1) 58 (15.4) 70 (18.8) 73 (25.3) 44 (30.8) 29 (19.9)
Hypercholesterolemia 78 (16.4) 45 (19.5) 33 (13.5) 937 (24.2) 484 (25.1) 453 (23.4) 205 (27.4) 103 (27.4) 102 (27.4) 81 (28.0) 42 (29.4) 39 (26.7)
Hypertension 130 (27.3) 67 (29.0) 63 (25.7) 1601 (41.4) 787 (40.7) 814 (42.1) 378 (50.5) 204 (54.3) 174 (46.8) 169 (58.5) 89 (62.2) 80 (54.8)
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