Rates of major bleeding were numerically lower with apixaban versus enoxaparin/warfarin across BMI categories (Pinteraction = .66)
| BMI category | Apixaban n/N |
Enoxaparin/Warfarin n/N |
RR (95% CI) | P interaction |
|
|---|---|---|---|---|---|
| ≤25 kg/m2 | 5/725 | 12/711 |
|
0.41 (0.15-1.18) | .66 |
| >25 kg/m2 to 30 kg/m2 | 7/999 | 17/1029 |
|
0.43 (0.18-1.02) | |
| >30 kg/m2 to 35 kg/m2 | 1/575 | 8/587 |
|
0.13 (0.02-1.01) | |
| >35 kg/m2 to 40 kg/m2 | 1/236 | 8/206 |
|
0.12 (0.02-0.85) | |
| >40 kg/m2 | 1/126 | 4/137 |
|
0.27 (0.03-2.40) |
Favors apixaban
Favors enoxaparin/warfarin
