• A total of 281 patients had apixaban plasma concentrations measured
  • A modest decrease (<30%) was seen in the median predicted exposure with increasing body weight
  • Exposure range was similar among body weight categories with overlapping quartiles
Predicted steady-state daily AUC
(ng*hr/mL)
8000
6000
4000
2000
0
2990
2734
2239
2006
≤ 60 kg
(n = 16)
> 60 to < 100 kg
(n = 199)
≥ 100 to < 120 kg
(n = 45)
≥ 120 kg
(n = 21)