Rates of major or CRNM bleeding were significantly lower in apixaban-treated patients compared with enoxaparin/warfarin-treated patients
across BMI categories (Pinteraction = .55)
BMI category Apixaban
n/N
Enoxaparin/Warfarin
n/N
  RR (95% CI) P
interaction
≤25 kg/m2 35/725 60/711
 
0.58 (0.38-0.86) .55
>25 kg/m2 to 30 kg/m2 33/999 89/1029
 
0.38 (0.26-0.56)
>30 kg/m2 to 35 kg/m2 29/575 64/587
 
0.46 (0.30-0.71)
>35 kg/m2 to 40 kg/m2 12/236 29/206
 
0.35 (0.18-0.66)
>40 kg/m2 5/126 17/137
 
0.32 (0.12-0.84)
0
0.5
1
1.5
2
1|2