Characteristic Apixaban
(n = 314)		 Warfarin
(n = 785)		 P value
Past medical history, n (%)
History of VTE 70 (22.3) 305 (38.9) <.01
History of bleeding 7 (2.2) 24 (3.1) .55
History of trauma in the prior 6 months 4 (1.3) 18 (2.3) .35
History of surgery in the prior 6 months 21 (6.7) 29 (3.7) .04
Liver disease 13 (4.1) 35 (4.5) .87
Index admission laboratory values, mean ± SD
Lowest platelet count (K/cmm) 198 ± 77 199 ± 77 .91
Lowest hemoglobin count (mg/dL) 10.9 ± 2.6 10.7 ± 2.3 .03
Discharge serum creatinine (mg/dL) 1.40 ± 1.55 1.27 ± 1.31 .05
Length of initial hospital stay (days), mean ± SD 6.5 ± 7.2 8.5 ± 8.8 .09
Concomitant medications at discharge, n (%)
NSAIDs 21 (6.7) 57 (7.3) .80
Aspirin 99 (31.5) 251 (32.0) .94
Clopidogrel 25 (8.0) 40 (5.1) .09
Prasugrel 0 0 –
Ticagrelor 1 (0.3) 1 (0.1) .49
Estrogen therapy 1 (0.3) 6 (0.8) .68
Cilostazol 1 (0.3) 5 (0.6) .68
SSRI/SNRI 48 (15.3) 148 (18.9) .19
1|2