• Retrospective design and potential lack of follow-up data to confirm VTE recurrence or bleeding events
    • The reliability of the results dependent on complete and accurate documentation within the EHR
  • Inability to collect information on the duration of anticoagulation, adherence, or outcome events in the outpatient setting, potential confounding comorbid diseases not included in our baseline data, time in therapeutic INR range for those on warfarin, reason for hospital encounters, and may not have captured events that did not result in a hospitalization or an emergency department visit