| Variable | HR | 95% CI | P value |
|---|---|---|---|
| Apixaban versus warfarin | 0.54 | 0.29-0.97 | .04 |
| Age | 0.98 | 0.96-0.99 | <.01 |
| BMI | 1.01 | 0.99-1.03 | 1.01 |
| Gender | 1.10 | 0.70-1.73 | .68 |
| Alcohol use disorder | 0.61 | 0.15-2.50 | .49 |
| Active cancer | 0.46 | 0.11-1.87 | .28 |
| Diabetes mellitus | 0.92 | 0.58-1.47 | .73 |
| History of stroke | 1.06 | 0.38-2.95 | .91 |
| History of VTE | 0.79 | 0.49-1.27 | .33 |
| Coagulation disorder | 1.53 | 0.82-2.85 | .18 |
| Concomitant clopidogrel use | 1.77 | 0.75-4.19 | .19 |
| History of surgical intervention | 0.60 | 0.15-2.47 | .48 |
| Admission for trauma/surgery | 1.24 | 0.44-3.44 | .69 |
| Stepwise regression with backward elimination | |||
| Apixaban vs warfarin | 0.53 | 0.30-0.95 | .03 |
| Age | 0.98 | 0.96-0.99 | <.01 |