Rates of major or CRNM bleeding were significantly lower in apixaban-treated patients compared with enoxaparin/warfarin-treated patients across body weight categories (Pinteraction = .36)
| Body weight category | Apixaban n/N |
Enoxaparin/Warfarin n/N |
RR (95% CI) | P interaction |
|
|---|---|---|---|---|---|
| ≤60 kg | 12/230 | 27/243 |
|
0.46 (0.24-0.89) | .36 |
| >60 kg to <100 kg | 86/1920 | 176/1924 |
|
0.49 (0.38-0.63) | |
| ≥100 kg to <120 kg | 11/377 | 36/372 |
|
0.30 (0.16-0.58) | |
| ≥120 kg | 6/144 | 22/146 |
|
0.28 (0.12-0.66) |
