BMI >40 kg/m2
All-cause mortality
Apix vs dabi
Apix vs riva
Dabi vs riva
Apix vs warfarin
Dabi vs warfarin
Riva vs warfarin
Myocardial infarction
Apix vs dabi
Apix vs riva
Dabi vs riva
Apix vs warfarin
Dabi vs warfarin
Riva vs warfarin
Ischemic stroke
Apix vs dabi
Apix vs riva
Dabi vs riva
Apix vs warfarin
Dabi vs warfarin
Riva vs warfarin
HR (95% CI)
0.0
0.2
0.4
0.6
0.8
1.0
1.2
1.4
1.6
1.8
2.0
BMI >40 kg/m2
Any bleeding
Apix vs dabi
Apix vs riva
Dabi vs riva
Apix vs warfarin
Dabi vs warfarin
Riva vs warfarin
GI bleeding
Apix vs dabi
Apix vs riva
Dabi vs riva
Apix vs warfarin
Dabi vs warfarin
Riva vs warfarin
Hemorrhagic stroke
Apix vs dabi
Apix vs riva
Dabi vs riva
Apix vs warfarin
Dabi vs warfarin
Riva vs warfarin
Heart failure
Apix vs dabi
Apix vs riva
Dabi vs riva
Apix vs warfarin
Dabi vs warfarin
Riva vs warfarin
HR (95% CI)
0.0
0.2
0.4
0.6
0.8
1.0
1.2
1.4
1.6
1.8
2.0
No head-to-head clinical trials have been conducted comparing the efficacy and safety of DOACs versus DOACs.
