No. of patients (incidence rate/100
person-years)		 Hazard ratio (95% CI) P value
Apixaban
(n=13,604)		 Warfarin
(n=12,918)
Stroke/SE 147 (1.51) 218 (2.09)
 
 0.82 (0.66–1.03) .088
Ischemic 109 (1.12) 148 (1.43)
 
 0.91 (0.70-1.18) .479
Hemorrhagic 29 (0.30) 56 (0.55)
 
 0.60 (0.37-0.99) .045
SE <11† 17 (0.17)
 
 0.61 (0.27-1.41) .249
MB 398 (4.06) 779 (7.27)
 
 0.62 (0.54-0.70) <.001
GI bleeding 210 (2.16) 384 (3.66)
 
 0.65 (0.54-0.77) <.001
ICH 68 (0.70) 163 (1.57)
 
 0.52 (0.38-0.70) <.001
Bleeding at other sites 164 (1.68) 320 (3.06)
 
 0.60 (0.49-0.74) <.001
0
0.5
1.0
1.5


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