Warfarin cohort (reference) | Apixaban cohort | Warfarin cohort (reference) | Dabigatran cohort | Warfarin cohort (reference) | Rivaroxaban cohort | |||||||
N/Mean | %/SD | N/Mean | %/SD | N/Mean | %/SD | N/Mean | %/SD | N/Mean | %/SD | N/Mean | %/SD | |
Sample size | 6310 | 100% | 6310 | 100% | 2342 | 100% | 2342 | 100% | 8055 | 100% | 8055 | 100% |
Age | 71.2 | 8.7 | 71.2 | 8.9 | 69.7 | 8.9 | 69.6 | 8.9 | 70.7 | 8.8 | 70.7 | 8.8 |
Gender | ||||||||||||
Male | 2859 | 45.3% | 2862 | 45.4% | 1143 | 48.8% | 1142 | 48.8% | 3689 | 45.8% | 3703 | 46.0% |
US geographic region* | ||||||||||||
Northeast | 1091 | 17.3% | 1064 | 16.9% | 455 | 19.4% | 461 | 19.7% | 1377 | 17.1% | 1413 | 17.5% |
North Central | 1785 | 28.3% | 1783 | 28.3% | 622 | 26.6% | 649 | 27.7% | 2387 | 29.6% | 2347 | 29.1% |
South | 2592 | 41.1% | 2594 | 41.1% | 911 | 38.9% | 899 | 38.4% | 3082 | 38.3% | 3118 | 38.7% |
West | - | - | 852 | 13.5% | - | - | 321 | 13.7% | - | - | 1158 | 14.4% |
Other | - | - | 17 | 0.3% | - | - | 12 | 0.5% | - | - | 19 | 0.2% |
Race (only for Humana and Medicare) | ||||||||||||
White | 4462 | 88.4% | 4451 | 88.2% | 1513 | 87.4% | 1505 | 86.9% | 5573 | 87.9% | 5579 | 88.0% |
Black | 399 | 7.9% | 411 | 8.1% | 162 | 9.4% | 157 | 9.1% | 502 | 7.9% | 505 | 8.0% |
Other | 184 | 2.9% | 183 | 2.9% | 56 | 2.4% | 69 | 2.9% | 263 | 3.3% | 254 | 3.2% |
Baseline comorbidity | ||||||||||||
Deyo-Charlson Comorbidity Index | 4.5 | 3.0 | 4.4 | 3.0 | 4.1 | 2.9 | 4.0 | 2.9 | 4.3 | 3.0 | 4.3 | 3.0 |