Probability of stroke/SE
at 2 Years
12
10
8
6
4
2
0
Weight (kg)
40
60
80
100
120
140
Stroke/SE
Interaction P value = .6401
Apixaban
Warfarin
Probability of all-cause
death at 2 years
20
16
12
8
4
0
Weight (kg)
40
60
80
100
120
140
All-Cause Death
Interaction P value = .3614
Apixaban
Warfarin
Probability of MI at 2 years
3.0
2.5
2.0
1.5
1.0
0.5
0
Weight (kg)
40
60
80
100
120
140
Myocardial Infarction
Interaction P value = .8694
Apixaban
Warfarin
Probability of ISTH major
bleeding at 2 years
12
10
8
6
4
2
0
Weight (kg)
40
60
80
100
120
140
ISTH Major Bleeding
Interaction P value = .0158
Apixaban
Warfarin
1|2|3|4|5