AUC (ng*hr/mL)
10,000
8000
6000
4000
2000
0
Body weight (kg)
50
100
150
200
Relationship between body weight and apixaban exposure in 2804 patients with NVAF receiving apixaban 5 mg bid in the ARISTOTLE trial.
-Triangles = female (n = 915);
-Circles = male (n = 1889).
