RR (95% CI) | |||||
---|---|---|---|---|---|
Outcomes | Apixaban 2.5 mg BID N = 840 |
Apixaban 5 mg BID N = 813 |
Placebo N = 829 |
Apixaban 2.5 mg BID vs placebo |
Apixaban 5 mg BID vs placebo |
Recurrent VTE or all-cause death | 32 (3.8) | 34 (4.2) | 96 (11.6) | 0.33 (0.22-0.48) P <.0001 |
0.36 (0.25-0.53) P <.0001 |
DVT* | 19 (2.3) | 28 (3.4) | 72 (8.7) | ||
PE* | 23 (2.7) | 25 (3.1) | 37 (4.5) | ||
All-cause death | 22 (2.6) | 25 (3.1) | 33 (4.0) | ||
Recurrent VTE or VTE-related death† | 14 (1.7) | 14 (1.7) | 73 (8.8) | 0.19 (0.11-0.33) |
0.20 (0.11-0.34) |