RR (95% CI)
Outcomes Apixaban
2.5 mg BID
N = 840
Apixaban
5 mg BID
N = 813
Placebo
N = 829
Apixaban
2.5 mg BID
vs placebo
Apixaban
5 mg BID
vs placebo
Recurrent VTE or all-cause death 32 (3.8) 34 (4.2) 96 (11.6) 0.33
(0.22-0.48)
P <.0001
0.36
(0.25-0.53)
P <.0001
DVT* 19 (2.3) 28 (3.4) 72 (8.7)
PE* 23 (2.7) 25 (3.1) 37 (4.5)
All-cause death 22 (2.6) 25 (3.1) 33 (4.0)
Recurrent VTE or VTE-related death 14 (1.7) 14 (1.7) 73 (8.8) 0.19
(0.11-0.33)
0.20
(0.11-0.34)